Pathobiology of avian influenza in domestic ducks

2016 ◽  
pp. 337-362
Author(s):  
Mary J. Pantin-Jackwood
2011 ◽  
Vol 157 (2) ◽  
pp. 247-257 ◽  
Author(s):  
Naoki Nomura ◽  
Yoshihiro Sakoda ◽  
Mayumi Endo ◽  
Hiromi Yoshida ◽  
Naoki Yamamoto ◽  
...  

Virus Genes ◽  
2019 ◽  
Vol 55 (3) ◽  
pp. 411-414
Author(s):  
Cheng Peng ◽  
Guangyu Hou ◽  
Jinping Li ◽  
Shanju Cheng ◽  
Suchun Wang ◽  
...  

2008 ◽  
Vol 82 (22) ◽  
pp. 11374-11382 ◽  
Author(s):  
Jeong-Ki Kim ◽  
Patrick Seiler ◽  
Heather L. Forrest ◽  
Alexey M. Khalenkov ◽  
John Franks ◽  
...  

ABSTRACT Waterfowl represent the natural reservoir of all subtypes of influenza A viruses, including H5N1. Ducks are especially considered major contributors to the spread of H5N1 influenza A viruses because they exhibit diversity in morbidity and mortality. Therefore, as a preventive strategy against endemic as well as pandemic influenza, it is important to reduce the spread of H5N1 influenza A viruses in duck populations. Here, we describe the pathogenicity of dominant clades (clades 1 and 2) of H5N1 influenza A viruses circulating in birds in Asia. Four representatives of dominant clades of the viruses cause symptomatic infection but lead to different profiles of lethality in domestic ducks. We also demonstrate the efficacy, cross-protectiveness, and immunogenicity of three different inactivated oil emulsion whole-virus H5 influenza vaccines (derived by implementing reverse genetics) to the viruses in domestic ducks. A single dose of the vaccines containing 1 μg of hemagglutinin protein provides complete protection against a lethal A/Duck/Laos/25/06 (H5N1) influenza virus challenge, with no evidence of morbidity, mortality, or shedding of the challenge virus. Moreover, two of the three vaccines achieved complete cross-clade or cross-subclade protection against the heterologous avian influenza virus challenge. Interestingly, the vaccines induce low or undetectable titers of hemagglutination inhibition (HI), cross-HI, and/or virus neutralization antibodies. The mechanism of complete protection in the absence of detectable antibody responses remains an open question.


2017 ◽  
Vol 5 (5) ◽  
Author(s):  
Guangyu Hou ◽  
Jinping Li ◽  
Cheng Peng ◽  
Suchun Wang ◽  
Jiming Chen ◽  
...  

ABSTRACT Here, we report the complete genome sequence of an H6N8 avian influenza virus (AIV) isolated from wild waterfowl in Poyang Lake, China, in 2016. Phylogenetic analysis showed that it was a novel reassortant AIV between domestic ducks and wild waterfowl. The finding of this study is helpful for our understanding of the ecology and the evolutionary characteristics of H6 subtypes of AIV in birds.


2007 ◽  
Vol 51 (s1) ◽  
pp. 429-431 ◽  
Author(s):  
John Pasick ◽  
Katherine Handel ◽  
John Robinson ◽  
Victoria Bowes ◽  
Yan Li ◽  
...  

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