Bio-Responsive Hydrogels for Biomedical Applications

Author(s):  
Tom McDonald ◽  
Alison Patrick ◽  
Richard Williams ◽  
Brian G. Cousins ◽  
Rein V. Ulijn
e-Polymers ◽  
2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Anna Korytkowska-Wałach ◽  
Anna Porwoł ◽  
Mirosław Gibas

AbstractA series of hydrogels were synthesized: homopolymers of new temperature-sensitive methacrylate macromonomers of ether-ester structure, derived from monomethacrylate of tetraethylene glycol via Michael-type addition - oligo(TTEGMMA), and copolymers of oligo(TTEGMMA) with N-isopropylacrylamide (NIPAAm) or 2-hydroxyethyl methacrylate (HEMA). Hydrogels based on oligo(TTEGMMA) demonstrate broad volume phase transition. Combination of oligo(TTEGMMA) with NIPAAm or HEMA yielded hydrogels having narrower phase transition and lower gel transition temperature (LGTT) up to 43 °C at the most, which is in the range of interest for most biomedical applications.


2017 ◽  
Vol 5 (5) ◽  
pp. 887-906 ◽  
Author(s):  
Xiaochu Ding ◽  
Yadong Wang

Here we define hydrogels crosslinked by weak bonds as physical hydrogels.


2021 ◽  
Vol 335 ◽  
pp. 541-556
Author(s):  
Zhenguang Li ◽  
Yingze Li ◽  
Chang Chen ◽  
Yu Cheng

2021 ◽  
pp. 100186
Author(s):  
Hussein M. El-Husseiny ◽  
Eman A. Mady ◽  
Lina Hamabe ◽  
Amira Abugomaa ◽  
Kazumi Shimada ◽  
...  

2014 ◽  
Vol 131 (23) ◽  
pp. n/a-n/a ◽  
Author(s):  
Kehinde Adesanya ◽  
Els Vanderleyden ◽  
Anika Embrechts ◽  
Piotr Glazer ◽  
Eduardo Mendes ◽  
...  

2020 ◽  
Vol 2 (3) ◽  
pp. 1092-1107 ◽  
Author(s):  
Jingsi Chen ◽  
Qiongyao Peng ◽  
Xuwen Peng ◽  
Linbo Han ◽  
Xiaogang Wang ◽  
...  

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Qiang Shi ◽  
Hao Liu ◽  
Deding Tang ◽  
Yuhui Li ◽  
XiuJun Li ◽  
...  

Abstract The increasingly intimate bond connecting soft actuation devices and emerging biomedical applications is triggering the development of novel materials with superb biocompatibility and a sensitive actuation capability that can reliably function as bio-use-oriented actuators in a human-friendly manner. Stimulus-responsive hydrogels are biocompatible with human tissues/organs, have sufficient water content, are similar to extracellular matrices in structure and chemophysical properties, and are responsive to external environmental stimuli, and these materials have recently attracted massive research interest for fabricating bioactuators. The great potential of employing such hydrogels that respond to various stimuli (e.g., pH, temperature, light, electricity, and magnetic fields) for actuation purposes has been revealed by their performances in real-time biosensing systems, targeted drug delivery, artificial muscle reconstruction, and cell microenvironment engineering. In this review, the material selection of hydrogels with multiple stimulus-responsive mechanisms for actuator fabrication is first introduced, followed by a detailed introduction to and discussion of the most recent progress in emerging biomedical applications of hydrogel-based bioactuators. Final conclusions, existing challenges, and upcoming development prospects are noted in light of the status quo of bioactuators based on stimulus-responsive hydrogels.


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