The Role of Nickel in Environmental Adaptation of the Gastric Pathogen Helicobacter pylori

2007 ◽  
pp. 545-579 ◽  
Author(s):  
Florian D. Ernst ◽  
Arnoud H. M. van Vliet ◽  
Manfred Kist ◽  
Johannes G. Kusters ◽  
Stefan Bereswill
Keyword(s):  
Helicobacter Pylori ◽  
Environmental Adaptation ◽  
Gastric Pathogen

The Emerging Role of Helicobacter Pylori-Induced Metabolic Gastrointestinal Dysmotility and Neurodegeneration

2018 ◽  
Vol 17 (6) ◽  
Author(s):  
J. Kountouras ◽  
M. Boziki ◽  
S.A. Polyzos ◽  
P. Katsinelos ◽  
E. Gavalas ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastrointestinal Dysmotility

scholarly journals Whole-Genome Sequencing and Comparative Genomics of Three Helicobacter pylori Strains Isolated from the Stomach of a Patient with Adenocarcinoma

Pathogens ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 331
Author(s):  
Montserrat Palau ◽  
Núria Piqué ◽  
M. José Ramírez-Lázaro ◽  
Sergio Lario ◽  
Xavier Calvet ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Whole Genome Sequencing ◽  
Genome Sequencing ◽  
Virulence Factors ◽  
Outer Membrane Proteins ◽  
Whole Genome ◽  
Flagellar Biosynthesis ◽  
H Pylori ◽  
Restriction Modification

Helicobacter pylori is a common pathogen associated with several severe digestive diseases. Although multiple virulence factors have been described, it is still unclear the role of virulence factors on H. pylori pathogenesis and disease progression. Whole genome sequencing could help to find genetic markers of virulence strains. In this work, we analyzed three complete genomes from isolates obtained at the same point in time from a stomach of a patient with adenocarcinoma, using multiple available bioinformatics tools. The genome analysis of the strains B508A-S1, B508A-T2A and B508A-T4 revealed that they were cagA, babA and sabB/hopO negative. The differences among the three genomes were mainly related to outer membrane proteins, methylases, restriction modification systems and flagellar biosynthesis proteins. The strain B508A-T2A was the only one presenting the genotype vacA s1, and had the most distinct genome as it exhibited fewer shared genes, higher number of unique genes, and more polymorphisms were found in this genome. With all the accumulated information, no significant differences were found among the isolates regarding virulence and origin of the isolates. Nevertheless, some B508A-T2A genome characteristics could be linked to the pathogenicity of H. pylori.

The role of linked color imaging in endoscopic diagnosis of Helicobacter pylori associated gastritis

2020 ◽  
Vol 55 (9) ◽  
pp. 1114-1120
Author(s):  
Sang Pyo Lee ◽  
Jin Lee ◽  
Sea Hyub Kae ◽  
Hyun Joo Jang ◽  
Dong Hee Koh ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Endoscopic Diagnosis ◽  
Color Imaging ◽  
Linked Color Imaging
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