Oxidative Splitting of Pyrimidine Cyclobutane Dimers

2004 ◽  
pp. 352-368
Author(s):  
Uta Wille
Keyword(s):  
Cyclobutane Dimers ◽  
Oxidative Splitting

scholarly journals DNA backbone conformation in cis-syn pyrimidine[]pyrimidine cyclobutane dimers

Biopolymers ◽  
1980 ◽  
Vol 19 (9) ◽  
pp. 1695-1701 ◽  
Author(s):  
S. Broyde ◽  
S. Stellman ◽  
B. Hingerty
Keyword(s):  
Backbone Conformation ◽  
Cyclobutane Dimers ◽  
Dna Backbone ◽  
In Cis

scholarly journals U-U and T-T cyclobutane dimers have different mutational properties

1993 ◽  
Vol 21 (17) ◽  
pp. 4059-4065 ◽  
Author(s):  
Peter E.M. Gibbs ◽  
Christopher W. Lawrence
Keyword(s):  
Cyclobutane Dimers

CHLORANIL-PHOTOSENSITIZED MONOMERIZATION OF DIMETHYLTHYMINE CYCLOBUTANE DIMERS and EFFECT OF MAGNESIUM PERCHLORATE

1990 ◽  
Vol 52 (5) ◽  
pp. 973-979 ◽  
Author(s):  
Chyongjin Pac ◽  
Ikuya Miyamoto ◽  
Yasuhiro Masaki ◽  
Seiichi Furusho ◽  
Shozo Yanagida ◽  
...  
Keyword(s):  
Magnesium Perchlorate ◽  
Cyclobutane Dimers

scholarly journals Requirement of DNA Polymerase η for Error-Free Bypass of UV-Induced CC and TC Photoproducts

2001 ◽  
Vol 21 (1) ◽  
pp. 185-188 ◽  
Author(s):  
Sung-Lim Yu ◽  
Robert E. Johnson ◽  
Satya Prakash ◽  
Louise Prakash
Keyword(s):  
Dna Polymerase ◽  
Uv Light ◽  
Wide Spectrum ◽  
Variant Form ◽  
Induced Mutations ◽  
Uv Mutagenesis ◽  
Genetic Studies ◽  
Human Dna ◽  
Skin Cancers ◽  
Cyclobutane Dimers

ABSTRACT The yeast RAD30-encoded DNA polymerase η (Polη) bypasses a cis-syn thymine-thymine dimer efficiently and accurately. Human DNA polymerase η functions similarly in the bypass of this lesion, and mutations in human Polη result in the cancer prone syndrome, the variant form of xeroderma pigmentosum. UV light, however, also elicits the formation ofcis-syn cyclobutane dimers and (6-4) photoproducts at 5′-CC-3′ and 5′-TC-3′ sites, and in both yeast and human DNA, UV-induced mutations occur primarily by 3′ C to T transitions. Genetic studies presented here reveal a role for yeast Polη in the error-free bypass of cyclobutane dimers and (6-4) photoproducts formed at CC and TC sites. Thus, by preventing UV mutagenesis at a wide spectrum of dipyrimidine sites, Polη plays a pivotal role in minimizing the incidence of sunlight-induced skin cancers in humans.

scholarly journals Catalyst Development for Water/CO2 Co-electrolysis

2019 ◽  
Vol 73 (9) ◽  
pp. 707-713
Author(s):  
Abhijit Dutta ◽  
Francesco Bizzotto ◽  
Jonathan Quinson ◽  
Alessandro Zana ◽  
Carina Elisabeth Morstein ◽  
...  
Keyword(s):  
Precious Metals ◽  
Electrolysis Cell ◽  
Half Cell ◽  
Catalytic Current ◽  
Electrochemical Conversion ◽  
Research Activities ◽  
Acidic Conditions ◽  
University Of Bern ◽  
The University ◽  
Oxidative Splitting

Herein, we discuss recent research activities on the electrochemical water/CO2 co-electrolysis at the Department of Chemistry and Biochemistry of the University of Bern (Arenz and Broekmann research groups). For the electrochemical conversion of the greenhouse gas CO2 into products of higher value catalysts for two half-cell reactions need to be developed, i.e. catalysts for the reductive conversion of CO2 (CO2RR) as well as catalysts for the oxidative splitting of water (OER: Oxygen Evolution Reaction). In research, the catalysts are often investigated independently of each other as they can later easily be combined in a technical electrolysis cell. CO2RR catalysts consist of abundant materials such as copper and silver and thus mainly the product selectivity of the respective catalyst is in focus of the investigation. In contrast to that, OER catalysts (in acidic conditions) mainly consist of precious metals, e.g. Ir, and therefore the minimization of the catalytic current per gram Ir is of fundamental importance.

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