Boron Clusters in Medical Applications

2005 ◽  
pp. 95-125 ◽  
Author(s):  
Detlef Gabel ◽  
Yasuyuki Endo
Keyword(s):  
Medical Applications ◽  
Boron Clusters

SARI : A User-Oriented Data Bank System for Medical Applications

1976 ◽  
Vol 15 (02) ◽  
pp. 69-74
Author(s):  
M. Goldberg ◽  
B. Doyon
Keyword(s):  
Data Base ◽  
Personal Data ◽  
Data Bank ◽  
Medical Applications ◽  
Basic Principles ◽  
Base Management ◽  
General Data ◽  
Privacy Problem ◽  
Bank System ◽  
Made In

This paper describes a general data base management package, devoted to medical applications. SARI is a user-oriented system, able to take into account applications very different by their nature, structure, size, operating procedures and general objectives, without any specific programming. It can be used in conversational mode by users with no previous knowledge of computers, such as physicians or medical clerks.As medical data are often personal data, the privacy problem is emphasized and a satisfactory solution implemented in SARI.The basic principles of the data base and program organization are described ; specific efforts have been made in order to increase compactness and to make maintenance easy.Several medical applications are now operational with SARI. The next steps will mainly consist in the implementation of highly sophisticated functions.

Self-calibrated surface acquisition for integrated positioning verification in medical applications

2019 ◽  
Vol 2019 (4) ◽  
pp. 353-1-353-9
Author(s):  
Sven Jörissen ◽  
Michael Bleier ◽  
Andreas Nüchter
Keyword(s):  
Medical Applications

Carborane Guests for Cucurbit[7]uril Facilitate Strong Binding and on Demand Removal

2020 ◽  
Author(s):  
Anna Kataki-Anastasakou ◽  
Jonathan C. Axtell ◽  
Selena Hernandez ◽  
RafalM. Dziedzic ◽  
Gary J. Balaich ◽  
...  
Keyword(s):  
Free State ◽  
Stimuli Responsive ◽  
Additional Consideration ◽  
Boron Clusters ◽  
High Affinity ◽  
On Demand ◽  
Azide Anion ◽  
Strong Binding

High affinity guest have been reported for the macrocyclic host cucurbit[7]uril (CB[7]), enabling widespread applications, but preventing CB[7] materials from being returned to their guest-free state for reuse. Here we present polyhedral boron clusters (carboranes) as strongly-binding, yet easily removable, guests for CB[7]. Aided by a Pd-catalyzed coupling of an azide anion, we prepared boron-functionalized 9<i>-</i>amino and 9-ammonium modified <i>ortho-</i>carboranes that bind to CB[7] with a <i>K<sub>a</sub></i>=10<sup>10</sup> M<sup>-1</sup>. Upon treatment with base, the <i>ortho</i>-carboranes<i> </i>readily undergo deboronation to yield anionic <i>nido</i>-carborane, a poor guest of CB[7], facilitating recovery of guest-free CB[7]. We showcase the utility of the modified <i>ortho</i>-carborane guest by recycling a CB[7]-functionalized resin. With this report, we introduce stimuli-responsive decomplexation as an additional consideration in the design of high affinity host-guest complexes.

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