scholarly journals A multistatic and multifrequency novel approach for specular meteor radars to improve wind measurements in the MLT region

Radio Science ◽  
2015 ◽  
Vol 50 (5) ◽  
pp. 431-442 ◽  
Author(s):  
G. Stober ◽  
J. L. Chau
Keyword(s):  
Novel Approach ◽  
Wind Measurements ◽  
Mlt Region

Wind measurements of MLT region using the Platteville, CO MEDAC 50MHz meteor radar

2005 ◽  
Vol 67 (13) ◽  
pp. 1211-1215 ◽  
Author(s):  
Santiago de la Peña ◽  
Susan K. Avery ◽  
James P. Avery ◽  
Elías Lau ◽  
Diego Janches
Keyword(s):  
Meteor Radar ◽  
Wind Measurements ◽  
Mlt Region

scholarly journals A comparison of 11-year mesospheric and lower thermospheric winds determined by meteor and MF radar at 69 ° N

2017 ◽  
Vol 35 (4) ◽  
pp. 893-906 ◽  
Author(s):  
Sven Wilhelm ◽  
Gunter Stober ◽  
Jorge L. Chau
Keyword(s):  
Lower Thermosphere ◽  
Meridional Wind ◽  
Correction Factors ◽  
Data Set ◽  
Wind Measurements ◽  
Mesosphere And Lower Thermosphere ◽  
Thermospheric Winds ◽  
Good Agreement ◽  
Mlt Region ◽  
Mf Radar

Abstract. The Andenes Meteor Radar (MR) and the Saura Medium Frequency (MF) Radar are located in northern Norway (69° N, 16° E) and operate continuously to provide wind measurements of the mesosphere and lower thermosphere (MLT) region. We compare the two systems to find potential biases between the radars and combine the data from both systems to enhance altitudinal coverage between 60 and 110 km. The systems have altitudinal overlap between 78 and 100 km at which we compare winds and tides on the basis of hourly winds with 2 km altitude bins. Our results indicate reasonable agreement for the zonal and meridional wind components between 78 and 92 km. An exception to this is the altitude range below 84 km during the summer, at which the correlation decreases. We also compare semidiurnal and diurnal tides according to their amplitudes and phases with good agreement below 90 km for the diurnal and below 96 km for the semidiurnal tides. Based on these findings we have taken the MR data as a reference. By comparing the MF and MR winds within the overlapping region, we have empirically estimated correction factors to be applied to the MF winds. Existing gaps in that data set will be filled with weighted MF data. This weighting is done due to underestimated wind values of the MF compared to the MR, and the resulting correction factors fit to a polynomial function of second degree within the overlapping area. We are therefore able to construct a consistent and homogenous wind from approximately 60 to 110 km.

Burst of Unusual Quasi-10 day Wave During the 2019 Southern Sudden Stratospheric Warming

2021 ◽  
Author(s):  
Jack Wang ◽  
Scott Palo ◽  
Jeffrey Forbes ◽  
John Marino ◽  
Tracy Moffat-Griffin
Keyword(s):  
Southern Hemisphere ◽  
Planetary Wave ◽  
Wave Activity ◽  
Stratospheric Warming ◽  
Atmospheric Conditions ◽  
Meteor Radar ◽  
Sudden Stratospheric Warming ◽  
Zonal Wavenumber ◽  
Wind Measurements ◽  
Mlt Region

<div> <p>An unusual sudden stratospheric warming (SSW) occurred in the Southern hemisphere in September 2019. Ground-based and satellite observations show the presence of a transient westward-propagating quasi-10 day planetary wave with zonal wavenumber one during the SSW. The planetary wave activity maximizes in the MLT region approximately 10 days after the SSW onset. Analysis indicates the quasi-10 day planetary wave is symmetric about the equator which is contrary to theory for such planetary waves. </p> </div><div> <p>Observations from MLS and SABER provide a unique opportunity to study the global structure and evolution of the symmetric quasi-10 day wave with observations of both geopotential height and temperature during these unusual atmospheric conditions. The space-based measurements are combined with meteor radar wind measurements from Antarctica, providing a comprehensive view of the quasi-10 day wave activity in the southern hemisphere during this SSW. We will also present the results of our mesospheric and lower thermospheric analysis along with a preliminary analysis of the ionospheric response to these wave perturbations.</p> </div>

A Novel Approach to the Development of Squall Database for Mooring Response Based Analysis

2017 ◽  
Author(s):  
Alessio Mariani ◽  
Grant Elliott ◽  
Geoff Wake ◽  
James Whelan ◽  
Gus Jeans
Keyword(s):  
Offshore Structures ◽  
Lower Atmosphere ◽  
Daily Maximum ◽  
Novel Approach ◽  
Direct Measurements ◽  
Time Histories ◽  
Important Input ◽  
Wind Measurements ◽  
Design Loads ◽  
Substantial Change

This paper describes a novel approach to the characterisation of the winds associated with squall events. Squalls are short duration events during which wind speed increases rapidly and is often characterised by a substantial change in direction. Squalls are an important input for the design of offshore structures, particularly weather vaning facilities such as turret moored FPSO’s for which squalls may induce substantial mooring loads. This paper presents the development of a synthetic squall database covering 63 years and combining direct high resolution wind measurements together with weather balloon observations of the lower atmosphere and historical daily maximum wind gusts. The squall database was a key input into a mooring Response Based Analysis (RBA) of a turret moored FPSO located offshore North Western Australia. Details of the synthetic squall database development are presented including: regional squall regime characterization, direct measurements, identification of peak squall events from long term measured datasets, characterisation based on weather balloon observations, generation of representative synthetic time histories of squall events. The squall database, coupled with a conventional hindcast metocean database including associated wave and currents parameters, allowed characterization of the weather vaning performance of the FPSO and identification of design loads for mooring design purposes.

Copper-dependent ATP7B up-regulation drives the resistance of TMEM16A-overexpressing head-and-neck cancer models to platinum toxicity

2019 ◽  
Vol 476 (24) ◽  
pp. 3705-3719 ◽  
Author(s):  
Avani Vyas ◽  
Umamaheswar Duvvuri ◽  
Kirill Kiselyov
Keyword(s):  
Oxidative Stress ◽  
Head And Neck ◽  
Transcriptional Activation ◽  
Platinum Resistance ◽  
Mrna Levels ◽  
Strong Positive Correlation ◽  
Platinum Compounds ◽  
Copper Chelation ◽  
Novel Approach ◽  
Cancer Models

Platinum-containing drugs such as cisplatin and carboplatin are routinely used for the treatment of many solid tumors including squamous cell carcinoma of the head and neck (SCCHN). However, SCCHN resistance to platinum compounds is well documented. The resistance to platinum has been linked to the activity of divalent transporter ATP7B, which pumps platinum from the cytoplasm into lysosomes, decreasing its concentration in the cytoplasm. Several cancer models show increased expression of ATP7B; however, the reason for such an increase is not known. Here we show a strong positive correlation between mRNA levels of TMEM16A and ATP7B in human SCCHN tumors. TMEM16A overexpression and depletion in SCCHN cell lines caused parallel changes in the ATP7B mRNA levels. The ATP7B increase in TMEM16A-overexpressing cells was reversed by suppression of NADPH oxidase 2 (NOX2), by the antioxidant N-Acetyl-Cysteine (NAC) and by copper chelation using cuprizone and bathocuproine sulphonate (BCS). Pretreatment with either chelator significantly increased cisplatin's sensitivity, particularly in the context of TMEM16A overexpression. We propose that increased oxidative stress in TMEM16A-overexpressing cells liberates the chelated copper in the cytoplasm, leading to the transcriptional activation of ATP7B expression. This, in turn, decreases the efficacy of platinum compounds by promoting their vesicular sequestration. We think that such a new explanation of the mechanism of SCCHN tumors’ platinum resistance identifies novel approach to treating these tumors.

Collecting Words: A Clinical Example of a Morphology-Focused Orthographic Intervention

2020 ◽  
Vol 51 (3) ◽  
pp. 544-560 ◽  
Author(s):  
Kimberly A. Murphy ◽  
Emily A. Diehm
Keyword(s):  
Written Language ◽  
Morphological Knowledge ◽  
English Orthography ◽  
Word Level ◽  
Novel Approach ◽  
Language Pathology ◽  
The One ◽  
Critical Intervention ◽  
Reading And Spelling ◽  
Reading And Spelling Difficulties

Purpose Morphological interventions promote gains in morphological knowledge and in other oral and written language skills (e.g., phonological awareness, vocabulary, reading, and spelling), yet we have a limited understanding of critical intervention features. In this clinical focus article, we describe a relatively novel approach to teaching morphology that considers its role as the key organizing principle of English orthography. We also present a clinical example of such an intervention delivered during a summer camp at a university speech and hearing clinic. Method Graduate speech-language pathology students provided a 6-week morphology-focused orthographic intervention to children in first through fourth grade ( n = 10) who demonstrated word-level reading and spelling difficulties. The intervention focused children's attention on morphological families, teaching how morphology is interrelated with phonology and etymology in English orthography. Results Comparing pre- and posttest scores, children demonstrated improvement in reading and/or spelling abilities, with the largest gains observed in spelling affixes within polymorphemic words. Children and their caregivers reacted positively to the intervention. Therefore, data from the camp offer preliminary support for teaching morphology within the context of written words, and the intervention appears to be a feasible approach for simultaneously increasing morphological knowledge, reading, and spelling. Conclusion Children with word-level reading and spelling difficulties may benefit from a morphology-focused orthographic intervention, such as the one described here. Research on the approach is warranted, and clinicians are encouraged to explore its possible effectiveness in their practice. Supplemental Material https://doi.org/10.23641/asha.12290687

Abstract #709: E-Consults: A Novel Approach to Increase Access to Subspecialty Care in Endocrinology

2015 ◽  
Vol 21 ◽  
pp. 128
Author(s):  
Kaniksha Desai ◽  
Halis Akturk ◽  
Ana Maria Chindris ◽  
Shon Meek ◽  
Robert Smallridge ◽  
...  
Keyword(s):  
Novel Approach
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