Low- versus high-dose of radioiodine for thyroid remnant ablation in differentiated thyroid carcinoma after thyroidectomy

2015 ◽  
Author(s):  
Charoonsak Somboonporn ◽  
Chetta Ngamjarus ◽  
Kannika Chathum ◽  
Krisana Roysri
Keyword(s):  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
High Dose ◽  
Thyroid Remnant ◽  
Remnant Ablation

scholarly journals Thyroid remnant volume and Radioiodine ablation in Differentiated thyroid carcinoma

2015 ◽  
Vol 17 (1) ◽  
pp. 55-60
Author(s):  
Md Sayedur Rahman Miah ◽  
Md Reajul Islam ◽  
Tanjim Siddika
Keyword(s):  
Thyroid Carcinoma ◽  
Atomic Energy Commission ◽  
Thyroid Volume ◽  
Differentiated Thyroid Carcinoma ◽  
High Dose ◽  
Thyroid Remnant ◽  
Complete Ablation ◽  
Successful Ablation ◽  
Remnant Thyroid ◽  
Radioiodine Ablation

Aims: The aims of the study were to determine the thyroid remnant volume and to see the effect of radioiodine ablation on thyroid remnant volume. Methods: A retrospective analysis of seventy-one differentiated thyroid carcinoma patients treated with high dose radioiodine (I-131) for post surgical ablation of thyroid remnants were done in Institute of Nuclear Medicine & Allied Sciences, Comilla of Bangladesh Atomic Energy Commission. Female were 60 and male were 11 with female-male ration of 5.5:1. All patients enrolled during the period from January 2001 to December 2011. The age range of the patients was 15 years to 90 years. The thyroid remnant volumes were determined by SPECT scintigraphy. High dose radioiodine (I-131) ablations were done with doses ranged from 2.77 GBq (75mCi) to 5.55 GBq (175 mCi). A successful ablation was defined as the absence of activity in the thyroid bed on subsequent imaging studies. Results: Fifty-nine patients (83.1%) showed complete ablation and twelve (16.9%) showed partial ablation of thyroid remnants after radioiodine therapy. The remnant thyroid volume as determined from scintigraphic images was significantly different (p = 0.048) between them who were completely ablated and them who were partially ablated. It was also observed that in complete ablation, 52.5% had thyroid remnant volume <1.0 gm, 40.7% had 1.1 to 2.0 gm, 5.1% had 2.1 to 3.0 gm and 1.7% had > 3.0 gm. i.e., The smaller the volume of thyroid remnant, better the response and larger the volume, the poorer the response to radioiodine. Conclusions: Successful ablation of thyroid remnants significantly depends on their volume and the successful ablation is inversely related with thyroid remnant volume. DOI: http://dx.doi.org/10.3329/bjnm.v17i1.22492 Bangladesh J. Nuclear Med. 17(1): 55-60, January 2014

Evaluation of factors predict the efficacy of thyroid remnant ablation in patients with differentiated thyroid carcinoma

2014 ◽  
Author(s):  
Narin Nasiroglu Imga ◽  
Serhat Isik ◽  
Mehtap Navdar Basaran ◽  
Bercem Aycicek Dogan ◽  
Mazhar Muslum Tuna ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Thyroid Remnant ◽  
Remnant Ablation

scholarly journals Radioiodine thyroid remnant ablation in patients with differentiated thyroid carcinoma (DTC): prospective comparison of long-term outcomes of treatment with 30, 60 and 100 mCi

2010 ◽  
Vol 3 (1) ◽  
pp. 9 ◽  
Author(s):  
Aleksandra Kukulska ◽  
Jolanta Krajewska ◽  
Marzena Gawkowska-Suwińska ◽  
Zbigniew Puch ◽  
Ewa Paliczka-Cieslik ◽  
...  
Keyword(s):  
Thyroid Carcinoma ◽  
Differentiated Thyroid Carcinoma ◽  
Long Term Outcomes ◽  
Thyroid Remnant ◽  
Remnant Ablation ◽  
Prospective Comparison
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