scholarly journals Dermoscopic Appearance of Intraluminal Hematogenous and Lymphatic Patterns of Cutaneous Melanoma Metastases

2015 ◽  
Vol 151 (1) ◽  
pp. 103
Author(s):  
Maira Fonseca ◽  
Michael A. Marchetti ◽  
Maija H. Kiuru ◽  
Ashfaq A. Marghoob ◽  
Allan C. Halpern
Keyword(s):  
Cutaneous Melanoma ◽  
Melanoma Metastases ◽  
Cutaneous Melanoma Metastases

scholarly journals Combination of Pembrolizumab with Electrochemotherapy in Cutaneous Metastases from Melanoma: A Comparative Retrospective Study from the InspECT and Slovenian Cancer Registry

Cancers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 4289
Author(s):  
Luca G. Campana ◽  
Barbara Peric ◽  
Matteo Mascherini ◽  
Romina Spina ◽  
Christian Kunte ◽  
...  
Keyword(s):  
Cancer Registry ◽  
Immune Checkpoint ◽  
Cutaneous Melanoma ◽  
Immune Checkpoint Inhibitors ◽  
Checkpoint Inhibitors ◽  
Locoregional Therapy ◽  
Tumor Control ◽  
Melanoma Metastases ◽  
Melanoma Patients ◽  
Cutaneous Melanoma Metastases

Electrochemotherapy (ECT) is an effective locoregional therapy for cutaneous melanoma metastases and has been safely combined with immune checkpoint inhibitors in preliminary experiences. Since ECT is known to induce immunogenic cell death, its combination with immune checkpoint inhibitors might be beneficial. In this study, we aimed to investigate the effectiveness of ECT on cutaneous melanoma metastases in combination with pembrolizumab. We undertook a retrospective matched cohort analysis of stage IIIC–IV melanoma patients, included in the International Network for sharing practices of ECT (InspECT) and the Slovenian Cancer Registry. We compared the outcome of patients who received the following treatments: (a) pembrolizumab alone, (b) pembrolizumab plus ECT, and (c) ECT. The groups were matched for age, sex, performance status, and size of skin metastases. The local objective response rate (ORR) was higher in the pembrolizumab-ECT group than in the pembrolizumab group (78% and 39%, p < 0.001). The 1 year local progression-free survival (LPFS) rates were 86% and 51% (p < 0.001), and the 1 year systemic PFS rates were 64% and 39%, respectively (p = 0.034). The 1 year overall survival (OS) rates were 88% and 64%, respectively (p = 0.006). Our results suggest that skin-directed therapy with ECT improves superficial tumor control in melanoma patients treated with pembrolizumab. Interestingly, we observed longer PFS and OS in the pembrolizumab-ECT group than in the pembrolizumab group. These findings warrant prospective confirmation.

Different dermoscopic patterns of cutaneous melanoma metastases in the same patient

2017 ◽  
Vol 152 (3) ◽  
Author(s):  
Ginevra Pertusi ◽  
Benedetta Miglino ◽  
Rossana Tiberio ◽  
Federica Veronese ◽  
Roberto Giorgione ◽  
...  
Keyword(s):  
Cutaneous Melanoma ◽  
Melanoma Metastases ◽  
Cutaneous Melanoma Metastases

scholarly journals Response rates of cutaneous melanoma metastases to diphencyprone: A meta-analysis

2020 ◽  
Vol 83 (6) ◽  
pp. 1812-1813
Author(s):  
Matheus de Melo Lôbo ◽  
Vinícius Fernando Calsavara ◽  
Bruno Vita Ricci ◽  
Clovis Antonio Lopes Pinto ◽  
Eduardo Bertolli ◽  
...  
Keyword(s):  
Cutaneous Melanoma ◽  
Meta Analysis ◽  
Response Rates ◽  
Melanoma Metastases ◽  
Cutaneous Melanoma Metastases

Dermoscopy of cutaneous melanoma metastases: A color‐based pattern classification

2019 ◽  
Vol 46 (7) ◽  
pp. 564-569
Author(s):  
Jose Antonio Avilés‐Izquierdo ◽  
Cristina Ciudad‐Blanco ◽  
Alejandro Sánchez‐Herrero ◽  
Ana Mateos‐Mayo ◽  
Lula María Nieto‐Benito ◽  
...  
Keyword(s):  
Pattern Classification ◽  
Cutaneous Melanoma ◽  
Melanoma Metastases ◽  
Cutaneous Melanoma Metastases

scholarly journals Dermoscopic patterns of cutaneous melanoma metastases

2013 ◽  
Vol 53 (4) ◽  
pp. 404-412 ◽  
Author(s):  
Pietro Rubegni ◽  
Arianna Lamberti ◽  
Filomena Mandato ◽  
Roberto Perotti ◽  
Michele Fimiani
Keyword(s):  
Cutaneous Melanoma ◽  
Melanoma Metastases ◽  
Cutaneous Melanoma Metastases

Macular eruption revealing hypomelanotic cutaneous melanoma metastases: Diagnostic role of dermoscopy

2014 ◽  
Vol 70 (1) ◽  
pp. e7-e9
Author(s):  
Houda Hammami-Ghorbel ◽  
Damien Giacchero ◽  
Véronique Hofman ◽  
Gilles Poissonnet ◽  
Thierry Passeron ◽  
...  
Keyword(s):  
Cutaneous Melanoma ◽  
Melanoma Metastases ◽  
Diagnostic Role ◽  
Cutaneous Melanoma Metastases
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