scholarly journals Is Universal Pediatric Lipid Screening Justified?

JAMA ◽  
2012 ◽  
Vol 307 (3) ◽  
Author(s):  
Matthew W. Gillman ◽  
Stephen R. Daniels
Keyword(s):  
Lipid Screening

More Widespread Pediatric Lipid Screening Advised

2007 ◽  
Vol 37 (8) ◽  
pp. 13
Author(s):  
SARAH PRESSMAN LOVINGER
Keyword(s):  
Lipid Screening

An Assessment of the New Lipid Screening Guidelines: In Reply

PEDIATRICS ◽  
2008 ◽  
Vol 122 (4) ◽  
pp. 906-907
Author(s):  
Stephen R. Daniels ◽  
Frank R. Greer ◽  
Nicolas Stettler
Keyword(s):  
Screening Guidelines ◽  
Lipid Screening

scholarly journals Low frequency of primary lipid screening among Medicare patients with rheumatoid arthritis

2011 ◽  
Vol 63 (5) ◽  
pp. 1221-1230 ◽  
Author(s):  
Christie M. Bartels ◽  
Amy J. H. Kind ◽  
Christine Everett ◽  
Matthew Mell ◽  
Patrick McBride ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Low Frequency ◽  
Lipid Screening ◽  
Medicare Patients

Abstract 14681: Comparative Study Between International Guidelines in Detecting Pediatric Familial Hypercholesterolemia Through a Unique Community Health System in Kagawa, Japan

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Keiji Matsunaga ◽  
Asako Mizobuchi ◽  
Hayato Tada ◽  
Tsuyoshi Sasaki ◽  
Yoshihiro Asano ◽  
...  
Keyword(s):  
Health System ◽  
Community Health ◽  
Familial Hypercholesterolemia ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Hereditary Disease ◽  
International Guidelines ◽  
Number Of Children ◽  
Lipid Clinic ◽  
Lipid Screening

Introduction: Familial hypercholesterolemia (FH) is an autosomal hereditary disease found in patients who have elevated low-density lipoprotein cholesterol (LDL-C) from birth. Early detection and treatment of FH during childhood potentially reduces the risk of premature cardiovascular events. In Kagawa prefecture, a unique community health system, involving three steps, has been conducted to prevent lifestyle-related diseases for 10-year-old children. This system includes universal lipid screening, selection by pediatricians, and next-generation sequencing (NGS) of FH-related genes in hospitals. The aim of this study is to compare 3 international guidelines to detect pediatric FH with this unique community health system in Kagawa. Methods: In Kagawa prefecture, the universal lipid screening of approximately 8,000 children at 10 years of age is performed annually, covering over 90% of the target group. After excluding secondary hypercholesterolemia, pediatric clinics introduced children with LDL-C >140mg/dL to 4 designated hospitals to perform NGS. We applied the guidelines of the Dutch Lipid Clinic Network (DLCN), Simon Broome (SB), and the Japanese Atherosclerosis Society (JAS) to children who received NGS in the unique community health system in Kagawa. Results: We performed NGS for 46 children from January 2018 to February 2020 (LDL-C 186.0±50.3 mg/dL; Male/F 27/19) and 26 (57%) had FH genetic mutations (23 LDL-R and 3 PCSK9 mutations). Seventeen children met FH criteria for DLCN (35%), 10 for Simon Broome (22%), and 11 for JAS (24%), respectively. The combination of NGS and either of the 3 guidelines increased the number of children diagnosed as FH up to 31 (67%). Conclusion: International guidelines detected only half of pediatric FH who were diagnosed by the unique community health system in Kagawa. Further investigation will be required to build an effective universal screening system for pediatric FH.

Lipid screening: Is measuring cholesterol enough?

1993 ◽  
Vol 60 (2) ◽  
pp. 115-116 ◽  
Author(s):  
J. P. Cooke ◽  
A. H. Singer
Keyword(s):  
Lipid Screening

Lipid Screening Patterns in an Urban Population

2020 ◽  
Vol 14 (4) ◽  
pp. 605-606
Author(s):  
Dipika Gopal ◽  
Reed Mszar ◽  
Daniel Soffer ◽  
Srinivas Denduluri ◽  
Richard Nemiroff ◽  
...  
Keyword(s):  
Urban Population ◽  
Lipid Screening

Lipid screening and lipoprotein electrophoresis by cellogel

1972 ◽  
Vol 36 (1) ◽  
pp. 51-60 ◽  
Author(s):  
H.J.M. Messerschmidt ◽  
Philip D.J.W. Sedee
Keyword(s):  
Lipid Screening
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