scholarly journals Effect of Dietary Protein Content on Weight Gain, Energy Expenditure, and Body Composition During Overeating

JAMA ◽  
2012 ◽  
Vol 307 (1) ◽  
pp. 47 ◽  
Author(s):  
George A. Bray ◽  
Steven R. Smith ◽  
Lilian de Jonge ◽  
Hui Xie ◽  
Jennifer Rood ◽  
...  
2008 ◽  
Vol 105 (1) ◽  
pp. 58-64 ◽  
Author(s):  
Joseph A. Alemany ◽  
Bradley C. Nindl ◽  
Mark D. Kellogg ◽  
William J. Tharion ◽  
Andrew J. Young ◽  
...  

Energy restriction coupled with high energy expenditure from arduous work is associated with an altered insulin-like growth factor-I (IGF-I) system and androgens that are coincident with losses of fat-free mass. The aim of this study was to determine the effects of two levels of dietary protein content and its effects on IGF-I, androgens, and losses of fat-free mass accompanying energy deficit. We hypothesized that higher dietary protein content would attenuate the decline of anabolic hormones and, thus, prevent losses of fat-free mass. Thirty-four men [24 (SD 0.3) yr, 180.1 (SD 1.1) cm, and 83.0 (SD 1.4) kg] participated in an 8-day military exercise characterized by high energy expenditure (16.5 MJ/day), low energy intake (6.5 MJ/day), and sleep deprivation (4 h/24 h) and were randomly divided into two dietary groups: 0.9 and 0.5 g/kg dietary protein intake. IGF-I system analytes, androgens, and body composition were assessed before and on days 4 and 8 of the intervention. Total, free, and nonternary IGF-I and testosterone declined 50%, 64%, 55%, and 45%, respectively, with similar reductions in both groups. There was, however, a diet × time interaction on day 8 for total IGF-I and sex hormone-binding globulin. Decreases in body mass (3.2 kg), fat-free mass (1.2 kg), fat mass (2.0 kg), and percent body fat (1.5%) were similar in both groups ( P = 0.01). Dietary protein content of 0.5 and 0.9 g/kg minimally attenuated the decline of IGF-I, the androgenic system, and fat-free mass during 8 days of negative energy balance associated with high energy expenditure and low energy intake.


2016 ◽  
Vol 48 (3) ◽  
pp. 741-751 ◽  
Author(s):  
Yuniel Méndez-Martínez ◽  
Stig Yamasaki-Granados ◽  
Marcelo U García-Guerrero ◽  
Luis R Martínez-Córdova ◽  
Marta E Rivas-Vega ◽  
...  

2015 ◽  
Vol 4 ◽  
Author(s):  
S. Ware ◽  
J.-P. Voigt ◽  
S. C. Langley-Evans

AbstractFetal exposure to maternal undernutrition has lifelong consequences for physiological and metabolic function. Maternal low-protein diet is associated with an age-related phenotype in rats, characterised by a period of resistance to development of obesity in early adulthood, giving way to an obesity-prone, insulin-resistant state in later adulthood. Offspring of rats fed a control (18 % casein) or low-protein (9 % casein; LP) diet in pregnancy were challenged with a high-fat diet at 9 months of age. To assess whether other maternal factors modulated the programming effects of nutrition, offspring were studied from young (2–4 months old) and older (6–9 months old) mothers. Weight gain with a high-fat diet was attenuated in male offspring of older mothers fed LP (interaction of maternal age and diet; P = 0·011) and adipose tissue deposition was lower with LP feeding in both males and females (P < 0·05). Although the resistance to weight gain and adiposity was partially explained by lower energy intake in offspring of LP mothers (P < 0·001 males only), it was apparent that energy expenditure must be influenced by maternal diet and age. Assessment of locomotor activity indicated that energy expenditure associated with physical activity was unlikely to explain resistance to weight gain, but showed that offspring of older mothers were more anxious than those of younger mothers, with more rearing observed in a novel environment and on the elevated plus-maze. The data showed that in addition to maternal undernutrition, greater maternal age may influence development and long-term body composition in the rat.


1983 ◽  
Vol 36 (3) ◽  
pp. 415-423 ◽  
Author(s):  
R. G. Campbell ◽  
A. C. Dunkin

ABSTRACTForty-five piglets were used to study the effects of feeding diets containing 153, 239 or 321 g crude protein per kg dry matter between 1·8 and 6·5 kg live weight, and low and high protein diets subsequent to 6·5 kg live weight on growth performance, body composition and the cellularity of skeletal muscle to 45 kg live weight.Reducing dietary crude protein between 1·8 and 6·5 kg live weight depressed growth performance and at 6·5 kg live weight increased body fat content but reduced body protein, body water and the weight and DNA content of the adductor muscle. The effects of dietary protein content before 6·5 kg live weight on body composition at the latter weight were still evident in pigs killed at 11·5 kg live weight whilst the differences in muscle DNA persisted to 45 kg live weight.On the lower protein treatment subsequent to 6·5 kg live weight there was a tendency for pigs given the lowest protein diet before 6-5 kg live weight to exhibit better growth performance and deposit protein at a faster rate than those given the higher protein diets. However, these responses were reversed on the higher protein treatment subsequent to 6·5 kg live weight.The effects of dietary protein content subsequent to 6·5 kg live weight on growth performance, body composition and the cellularity of muscle tissue were qualitatively the same as those for the live-weight phase 1·8 to 6·5 kg.


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