Acute Ischemic Stroke: Imaging and Intervention

JAMA ◽  
2011 ◽  
Vol 306 (19) ◽  
Author(s):  
Ian B. Ross
PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e113967
Author(s):  
Yuanqi Zhao ◽  
Min Zhao ◽  
Xiaomin Li ◽  
Xiancong Ma ◽  
Qinghao Zheng ◽  
...  

2012 ◽  
Vol 33 (9) ◽  
pp. 1791-1796 ◽  
Author(s):  
G. Parrilla ◽  
B. García-Villalba ◽  
M. Espinosa de Rueda ◽  
J. Zamarro ◽  
E. Carrión ◽  
...  

Stroke ◽  
2021 ◽  
Vol 52 (2) ◽  
Author(s):  
Gabriel Broocks ◽  
Jens Minnerup ◽  
Rosalie McDonough ◽  
Fabian Flottmann ◽  
Andre Kemmling

Stroke ◽  
2012 ◽  
Vol 43 (suppl_1) ◽  
Author(s):  
Ilana Spokoyny ◽  
Rema Raman ◽  
Karin Ernstrom ◽  
Brett C Meyer ◽  
Thomas M Hemmen

Background/Purpose: Intravenous Alteplase (t-PA) improves outcome in patients with acute ischemic stroke. Of those who recover fully, some may not have had ischemia. We analyzed the frequency and post-treatment outcomes of patients with no imaging evidence of stroke and aimed to delineate the frequency of strokes with full recovery from that of stroke mimics treated with t-PA. Methods: We included all adult stroke patients treated with IV t-PA within 3 hours of stroke onset from the UCSD SPOTRIAS database. Group 1: Patients with neuroimaging evidence of acute stroke (IPS); Group 2: no neuroimaging evidence of acute stroke (INS). All diagnoses were established by an independent adjudicating body. We reviewed medical records, neuroimaging, and compared discharge diagnosis, 90-day mRS, and incidence of intracranial hemorrhage. We adjusted for age, admission NIHSS, and pre-stroke mRS in multivariable models. Results: We identified 61patients with IPS and 25 with INS, with similar baseline characteristics, except for baseline NIHSS (IPS 13.4±8.2, INS 8.4±5.9, p=0.007) and incidence of cardiac arrhythmias (IPS 36.1%, INS 4.0%, p=0.002). Adjusted for age and baseline NIHSS, we found no difference in outcome. ICH was found in 23% of the IPS patients and was symptomatic in 4.9%. None of the INS patients had ICH. Conclusions: Radiologic evidence of acute ischemic stroke was absent in 10.5% of the 86 patients in the UCSD SPOTRIAS database who were treated with t-PA and given a clinical diagnosis of acute ischemic stroke on adjudicating body review at discharge. The majority (64%) of imaging negative stroke patients in our study ultimately received the clinical diagnosis of acute stroke. No significant difference in outcomes (mRS) was found between imaging negative and imaging positive stroke code patients, aside from the increased ICH frequency in imaging positive patients. This lack of outcome difference emphasizes that while imaging plays an important role as a surrogate marker in determining the diagnosis, a detailed clinical evaluation is essential in the correct treatment of acute ischemic stroke. Imaging negative stroke patients are common and future larger scale prospective data is required to analyze the true frequency of stroke mimics versus imaging negative stroke.


2014 ◽  
Vol 36 (1) ◽  
pp. E3 ◽  
Author(s):  
Elizabeth Tong ◽  
Qinghua Hou ◽  
Jochen B. Fiebach ◽  
Max Wintermark

Neuroimaging has expanded beyond its traditional diagnostic role and become a critical tool in the evaluation and management of stroke. The objectives of imaging include prompt accurate diagnosis, treatment triage, prognosis prediction, and secondary preventative precautions. While capitalizing on the latest treatment options and expanding upon the “time is brain” doctrine, the ultimate goal of imaging is to maximize the number of treated patients and improve the outcome of one the most costly and morbid disease. A broad overview of comprehensive multimodal stroke imaging is presented here to affirm its utilization.


2010 ◽  
Vol 31 (7) ◽  
pp. 1290-1296 ◽  
Author(s):  
A.D. Furtado ◽  
D.D. Adraktas ◽  
N. Brasic ◽  
S.-C. Cheng ◽  
K. Ordovas ◽  
...  

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