scholarly journals Nonsteroidal Anti-inflammatory Drugs and Postoperative Bleeding Following Adenotonsillectomy in Pediatric Patients

2008 ◽  
Vol 134 (1) ◽  
pp. 24 ◽  
Author(s):  
Anita Jeyakumar ◽  
Todd M. Brickman ◽  
Mary E. Williamson ◽  
Keiko Hirose ◽  
Paul Krakovitz ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Postoperative Bleeding ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Negative predictive value of provocation tests for nonsteroidal anti-inflammatory drugs in children

2020 ◽  
Vol 41 (4) ◽  
pp. 285-289 ◽  
Author(s):  
Ozge Yilmaz Topal ◽  
Kulhas C. Ilknur ◽  
Yagmur T. Irem ◽  
Toyran Muge ◽  
Civelek Ersoy ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Provocation Test ◽  
Allergy Clinic ◽  
Predictive Values ◽  
Pediatric Allergy ◽  
Provocation Tests ◽  
Drug Classes ◽  
Drug Provocation Test ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Background: After antibiotics, nonsteroidal anti-inflammatory drugs (NSAID) are one of the leading drug classes responsible for hypersensitivity reactions in children. The drug provocation test (DPT) is the criterion standard for diagnosis. Objective: The aim of the present study was to determine the negative predictive values (NPV) of DPTs with NSAIDs in pediatric patients and to evaluate their attitudes toward NSAID use after a negative DPT result. Methods: The study included all patients who had undergone DPTs between January 1, 2014, and December 31, 2018, in our pediatric allergy clinic for suspected NSAID hypersensitivity reaction and who had a negative result for the suspected agent. Those patients who could be contacted were asked whether the patient had used the same drug again since the DPT and, if so, whether he or she had a reaction. Patients who were reported to have had a reaction were invited to the clinic for reevaluation. Based on the findings from this retesting, the NPVs of the DPTs with NSAIDs were calculated. Results: During the 5-year study period, DPT results were negative for 230 suspected agents in 215 patients. Of these, 143 patients (66.5%) were able to be contacted. A total of 108 patients (75.5%) had used the tested NSAIDs at least once after the provocation test, and five patients (4.6%) reported a reaction on reexposure. Four of these patients declined reevaluation, one patient exhibited no reaction in a second DPT. Therefore, the NPV was calculated as 96.3% (94.3% for ibuprofen, and 100% for paracetamol). Conclusion: The NPVs of DPTs with NSAIDs, especially of paracetamol DPT, is high in children. This finding should reassure the parents of patients who may require NSAID therapy again.

The role of nonsteroidal anti-inflammatory drugs in pediatric patients

2012 ◽  
Vol 65 (1) ◽  
pp. 5-8 ◽  
Author(s):  
Robin Dills ◽  
Leigh A. Anderson ◽  
Catherine A. Pierce
Keyword(s):  
Pediatric Patients ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals Hypersensitivity to non-steroidal anti-inflammatory drugs in pediatric patients

2015 ◽  
Vol 8 ◽  
pp. A120
Author(s):  
Alex Lacerda ◽  
Luis Felipe Ensina ◽  
Ligia Maria Oliveira Machado ◽  
Dirceu Sole ◽  
Inês Cristina Camelo Nunes ◽  
...  
Keyword(s):  
Pediatric Patients ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals The place of aceclofenac in the preparation of patients with rheumatic diseases for joint surgery

2019 ◽  
Vol 13 (4) ◽  
pp. 124-129
Author(s):  
V. N. Amirdzhanova ◽  
A. E. Karateev
Keyword(s):  
Risk Factors ◽  
Postoperative Bleeding ◽  
Joint Diseases ◽  
Preoperative Preparation ◽  
Inflammatory Joint Diseases ◽  
Joint Surgery ◽  
Thrombotic Complications ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

To identify risk factors for gastrointestinal, cardiovascular, and thrombotic complications, as well as postoperative bleeding, by individually choosing analgesic anti-inflammatory therapy, including that with nonsteroidal anti-inflammatory drugs, is the most important task in the preoperative preparation of patients with rheumatic inflammatory joint diseases.The paper reviews studies evaluating the efficiency and safety of long-term aceclofenac use in patients who are to undergo joint surgery.

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