scholarly journals Association of Nonsteroidal Anti-inflammatory Drugs With First Occurrence of Heart Failure and With Relapsing Heart Failure

2002 ◽  
Vol 162 (3) ◽  
pp. 265 ◽  
Author(s):  
Johan Feenstra ◽  
Eibert R. Heerdink ◽  
Diederick E. Grobbee ◽  
Bruno H. Ch. Stricker
Keyword(s):  
Heart Failure ◽  
First Occurrence ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

scholarly journals The role of anti-inflammatory drugs and nanoparticle-based drug delivery models in the management of ischemia-induced heart failure

2021 ◽  
Vol 142 ◽  
pp. 112014
Author(s):  
Kathryn E. Haley ◽  
Talal Almas ◽  
Saeed Shoar ◽  
Shan Shaikh ◽  
Maimoona Azhar ◽  
...  
Keyword(s):  
Heart Failure ◽  
Drug Delivery ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Delivery Models

Association of outpatient utilisation of non-steroidal anti-inflammatory drugs and hospitalised heart failure in the entire Swedish population

2001 ◽  
Vol 57 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Juan Merlo ◽  
Kristian Broms ◽  
Ulf Lindblad ◽  
Agneta Björck-Linné ◽  
Hans Liedholm ◽  
...  
Keyword(s):  
Heart Failure ◽  
Swedish Population ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Prescriber responsibility, predictors for initiation, and 20-year trends in use of non-aspirin non-steroidal anti-inflammatory drugs in patients with cardiovascular contraindications: a nationwide cohort study

2020 ◽  
Author(s):  
Morten Schmidt ◽  
Anton Pottegård
Keyword(s):  
Heart Failure ◽  
Cardiovascular Disease ◽  
General Practitioners ◽  
Treatment Duration ◽  
St Segment Elevation ◽  
Disease Subtype ◽  
St Segment ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
One Year

Abstract Aims To examine whether prescription patterns complied with recommendations not to use non-steroidal anti-inflammatory drugs (NSAIDs) in patients with cardiovascular contraindications. Moreover, we examined predictors for initiation and prescriber responsibility. Methods and results We used Danish medical databases to identify all patients with first-time cardiovascular disease during 1996–2017 (n = 628 834). We assessed standardized prevalence proportions, predictors from logistic regression, and prescriber identifiers. One-year prevalence of NSAID initiation increased 3.4% from 1996 (19.4%) to 2001 (22.7%) and declined by 2.7% thereafter until 2017 (13.5%). Trends were independent of age, sex, and disease subtype, although larger annual declines occurred for heart failure (3.9%) and ischaemic heart disease (3.5%) since 2002. One-year prevalence remained highest among patients with venous thromboembolism (16.6%) and angina (13.8%), and lowest for ST-segment elevation myocardial infarction (7.0%) and heart failure (8.8%). Initiators were predominantly prescribed ibuprofen (59%), diclofenac (23%), and etodolac (6%). Diclofenac and coxib use declined, while ibuprofen and naproxen use increased. Median prescribed pill dose of ibuprofen declined after 2008 from moderate/high (600 mg) to low (400 mg). Treatment duration declined for all NSAIDs, except celecoxib. Rheumatic, obesity, and pain-related conditions predicted NSAID initiation. General practitioners issued 86–91% of all NSAID prescriptions, followed by hospital prescribers (7.3–12%). Conclusions Initiation of NSAIDs in patients with cardiovascular disease declined since 2002. Shorter treatment duration, declining COX-2 inhibition, and increasing use of naproxen and low-dose ibuprofen suggest adherence to guidelines when NSAIDs cannot be avoided. Still, NSAID use remained prevalent despite cardiovascular contraindications, warranting awareness of appropriateness of use among general practitioners in particular.

Nonsteroidal Anti-Inflammatory Drugs and Heart Failure

Drugs ◽  
2003 ◽  
Vol 63 (6) ◽  
pp. 525-534 ◽  
Author(s):  
Gys??le S Bleumink ◽  
Johannes Feenstra ◽  
Miriam C J M Sturkenboom ◽  
Bruno H Ch Stricker
Keyword(s):  
Heart Failure ◽  
Inflammatory Drugs ◽  
Anti Inflammatory
Sign in / Sign up

Export Citation Format

Share Document