Clinical and immunologic study of 205 patients with chronic fatigue syndrome: a case series from Italy

1993 ◽  
Vol 153 (1) ◽  
pp. 116-117 ◽  
Author(s):  
V. Tirelli
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Case Series ◽  
Chronic Fatigue ◽  
Fatigue Syndrome

scholarly journals High-frequency rTMS for the Treatment of Chronic Fatigue Syndrome: A Case Series

2016 ◽  
Vol 55 (23) ◽  
pp. 3515-3519 ◽  
Author(s):  
Wataru Kakuda ◽  
Ryo Momosaki ◽  
Naoki Yamada ◽  
Masahiro Abo
Keyword(s):  
Chronic Fatigue Syndrome ◽  
High Frequency ◽  
Case Series ◽  
Chronic Fatigue ◽  
Fatigue Syndrome

Characterising DSCATT: A case series of Australian patients with debilitating symptom complexes attributed to ticks

2021 ◽  
pp. 000486742110437
Author(s):  
Jesse Schnall ◽  
Georgina Oliver ◽  
Sabine Braat ◽  
Richard Macdonell ◽  
Katherine B Gibney ◽  
...  
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Lyme Disease ◽  
Case Series ◽  
Disease Process ◽  
Chronic Fatigue ◽  
Retrospective Case ◽  
Medical Diagnoses ◽  
Fatigue Syndrome ◽  
First Case ◽  
Medically Unexplained

Objectives(s): To characterise the clinical profile, aetiology and treatment responsiveness of ‘Australian Lyme’, or Debilitating Symptom Complexes Attributed to Ticks. Methods: Single-centre retrospective case analysis of patients referred to the Infectious Diseases Unit at Austin Health – a tertiary health service in Heidelberg, Australia – between 2014 and 2020 for investigation and treatment of suspected Debilitating Symptom Complexes Attributed to Ticks. Patients were included if they had debilitating symptoms suggested by either themselves or the referring clinician as being attributed to ticks. Results: Twenty-nine Debilitating Symptom Complexes Attributed to Ticks cases were included in the analysis. Other than Lyme disease (83%), the most common prior medical diagnoses were Epstein–Barr virus (38%), chronic fatigue syndrome (28%) and fibromyalgia (24%). Prior histories of anxiety (48%) and depression (41%) were common. The most frequently reported symptoms included fatigue (83%), headache (72%) and arthralgia (69%). National Association of Testing Authorities/Royal College of Pathologists of Australasia–accredited serology was not diagnostic of acute infective causes, including Lyme disease, in any patient. Of 25 cases with available data, 23 (92%) had previously been prescribed antimicrobials, with 53% reporting benefit from them. The most common diagnoses made by our hospital were chronic fatigue syndrome (31%), migraines (28%) and fibromyalgia (21%). Only one patient’s symptoms were not accounted for by other diagnoses. Conclusion: This is the first case series of patients with Debilitating Symptom Complexes Attributed to Ticks. They had high rates of other medically unexplained syndromes, and no evidence of acute Lyme disease, or any common organic disease process. Debilitating Symptom Complexes Attributed to Ticks remains medically unexplained, and may therefore be due to an as yet unidentified cause, or may be considered a medically unexplained syndrome similar to conditions such as chronic fatigue syndrome.

scholarly journals Association between quadrivalent human papillomavirus vaccination and selected syndromes with autonomic dysfunction in Danish females: population based, self-controlled, case series analysis

BMJ ◽  
2020 ◽  
pp. m2930 ◽  
Author(s):  
Anders Hviid ◽  
Nicklas M Thorsen ◽  
Palle Valentiner-Branth ◽  
Morten Frisch ◽  
Kåre Mølbak
Keyword(s):  
Human Papillomavirus ◽  
Chronic Fatigue Syndrome ◽  
Complex Regional Pain Syndrome ◽  
Autonomic Dysfunction ◽  
Case Series ◽  
Pain Syndrome ◽  
Chronic Fatigue ◽  
Postural Orthostatic Tachycardia Syndrome ◽  
Human Papillomavirus Vaccination ◽  
Fatigue Syndrome

Abstract Objective To evaluate the association between quadrivalent human papillomavirus vaccination and syndromes with autonomic dysfunction, such as chronic fatigue syndrome, complex regional pain syndrome, and postural orthostatic tachycardia syndrome. Design Population-based self-controlled case series. Setting Information on human papillomavirus vaccinations and selected syndromes with autonomic dysfunction (chronic fatigue syndrome, complex regional pain syndrome, and postural orthostatic tachycardia syndrome) identified using ICD-10 (international classification of diseases, revision 10) diagnostic codes from Danish nationwide registers. Participants 869 patients with autonomic dysfunction syndromes from a cohort of 1 375 737 Danish born female participants aged 10 to 44 years during 2007-16. Main outcome measures Self-controlled case series rate ratios (95% confidence intervals) of the composite outcome of chronic fatigue syndrome, complex regional pain syndrome, and postural orthostatic tachycardia syndrome, adjusted for age and season, comparing female participants vaccinated and unvaccinated with the quadrivalent human papillomavirus vaccine. Chronic fatigue syndrome, complex regional pain syndrome, and postural orthostatic tachycardia syndrome were also considered separately in secondary analyses. Results During 10 581 902 person years of follow-up, 869 female participants with syndromes of autonomic dysfunction (136 with chronic fatigue syndrome, 535 with complex regional pain syndrome, and 198 with postural orthostatic tachycardia syndrome) were identified. Quadrivalent human papillomavirus vaccination did not statistically significantly increase the rate of a composite outcome of all syndromes with autonomic dysfunction in a 365 day risk period following vaccination (rate ratio 0.99, 95% confidence interval 0.74 to 1.32) or the rate of any individual syndrome in the risk period (chronic fatigue syndrome (0.38, 0.13 to 1.09), complex regional pain syndrome (1.31, 0.91 to 1.90), or postural orthostatic tachycardia syndrome (0.86, 0.48 to 1.54)). Conclusions When vaccination is introduced, adverse events could occur in close temporal relation to the vaccine purely by chance. These results do not support a causal association between quadrivalent human papillomavirus vaccination and chronic fatigue syndrome, complex regional pain syndrome, or postural orthostatic tachycardia syndrome, either individually or as a composite outcome. An increased risk of up to 32% cannot be formally excluded, but the statistical power of the study suggests that a larger increase in the rate of any syndrome associated with vaccination is unlikely.

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