Normalization of abnormal T waves in ischemia

1976 ◽  
Vol 136 (4) ◽  
pp. 391-395 ◽  
Author(s):  
R. J. Noble
Keyword(s):  
T Waves

scholarly journals A new method of filtering T waves to detect hidden P waves in electrocardiogram signals

EP Europace ◽  
2011 ◽  
Vol 13 (7) ◽  
pp. 1028-1033 ◽  
Author(s):  
D. Goldwasser ◽  
A. Bayes de Luna ◽  
G. Serra ◽  
R. Elosua ◽  
E. Rodriguez ◽  
...  
Keyword(s):  
New Method ◽  
P Waves ◽  
Electrocardiogram Signals ◽  
T Waves

Peaked “T” Waves with Tranylcypromine (Parnate) Overdose

1982 ◽  
Vol 11 (2) ◽  
pp. 155-160 ◽  
Author(s):  
Timothy E. Quill
Keyword(s):  
Monoamine Oxidase ◽  
Intracranial Hemorrhage ◽  
Case Reports ◽  
Monoamine Oxidase Inhibitors ◽  
Toxic Effects ◽  
Recent Case ◽  
Clinical Use ◽  
Ecg Changes ◽  
T Waves

A case of tranylcypromine (Parnate) overdose is presented in which the main toxic effects were headache, obtundation, hypertension, and diffusely peaked T-waves on ECG. The latter effect, which occurred in the absence of hyperkalemia, has not been previously associated with monoamine oxidase inhibitors (MAOI). Recent case reports of tranylcypromine toxicity are briefly reviewed, confirming the potential for hypertension, hypotension, shock, hyperpyrexia, intracranial hemorrhage, agitation, hyperkinesis, coma and death in association with overdosage, or concommitant ingestion of sympathomimetic substances or other drugs. These ECG changes add to the worrisome list of potential toxicities in an era in which MAOI are finding increased clinical use.

Study on the Effects of Kuanxiong Aerosol on the Isolated Artery and Rabbits Acute Myocardial Ischemia Model

2021 ◽  
Vol 24 ◽  
Author(s):  
Xia Liu ◽  
Feihua Huang ◽  
Xiao Lu ◽  
Yuji Wang ◽  
Tingting Cai ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
Troponin T ◽  
Pharmacological Study ◽  
Acute Myocardial Ischemia ◽  
Chinese Herbal Compound ◽  
Long Acting ◽  
Traditional Chinese Medicine Preparation ◽  
T Waves

Background: Kuan xiong aerosol (KXA) is a kind of Chinese herbal compound used to regulating qi-flowing for relieving pain and improving angina. However, little pharmacological study of this traditional Chinese medicine preparation has been reported to confirm these activities. Objective: This article aims to observe the effect of resisting acute myocardial ischemia (AMI) in vivo and dilating vessel in vitro of KXA. Materials: The AMI model involves intravenously injecting pituitary (2 U.kg-1) into the ear of rabbits. Electrocardiograph (ECG) T waves were then recorded after administration and the falling range was calculated. Following this, the level of serum Cardiac troponin T (cTn-T) and the histopathology of the cardiac muscle tissue was evaluated. In vitro, the effect of KXA on vasodilation of isolated aortic rings that had been pre-contracted with KCl (30 mM) was observed. Results: It was found KXA reduced ECG ST-T waves and serum cTn-T in the rabbit AMI model, protected myocardial tissue from fracturing and loss of myocardial fibers, and inhibited inflammatory cell infiltration, cavitation degeneration and karyopyknosis of the myocardial matrix. Furthermore, the administration of 0.215, 1.075 and 2.150 mg.mL-1 KXA resulted in significant relaxation of the aortic rings at a rate of 69.63 %, 90.14 % and 118.72 % (p < 0.01) of the untreated ones, and a second shrinkage ratio of 20.17 %, 4.29 %, and 4.54 % (p < 0.01) of the untreated ones, respectively. Conclusions: these results suggest KXA protects against AMI, contributes to dilation of blood vessels and has long-acting effectiveness.

Abstract 3265: A Comparison of Echocardiographic and Electrocardiographic Characteristics of Patients with Apical Hypertrophic Cardiomyopathy

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Josepha Binder ◽  
Brandon R Grossardt ◽  
Christine Attenhofer Jost ◽  
Kyle W Klarich ◽  
Michael J Ackerman ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Ejection Fraction ◽  
Left Ventricular ◽  
Right Atrial ◽  
Apical Hypertrophic Cardiomyopathy ◽  
T Wave ◽  
Atrial Enlargement ◽  
Lv Ejection Fraction ◽  
The Relationship ◽  
T Waves

Background: Apical hypertrophic cardiomyopathy (apical HCM) is a less common subtype of HCM characterized by a focal thickening in the left ventricular apex. “Classic” ECG features have been described, however, apical HCM can persist for many years without detection. We investigated the relationship between ECG findings and echocardiographic morphometry in a large referral series of patients with apical HCM. Methods: We enumerated all patients diagnosed with apical HCM prior to Sept. 30, 2006 using the Mayo Clinic HCM database. We compared echocardiographic measures separately for patients with positive status for two ECG indices of left ventricular hypertrophy (LVH); the Sokolow-Lyon index and the Romhilt-Estes (RE) point-score. We also compared echocardiographic measurements in patients with and without negative T-waves in the precordial leads. Results: Apical HCM was detected in 177 patients (111 men and 68 women). Only 51% had positive Sokolow criteria and 51% had positive RE criteria. The agreement between Sokolow and RE status was high (agreement = 75.0%; kappa = 0.50; 95% CI = 0.38 – 0.62). In particular, Sokolow positive patients had increased LV ejection fraction (P = 0.02), and decreased LV end-systolic diameter (P = 0.03) compared with Sokolow negative patients. The prevalence of right atrial enlargement (47 vs. 28%; P = 0.02) and intracavity obstruction (22 vs. 8%; P = 0.01) were more common in Sokolow positive patients. Positive RE criteria was associated with a greater thickness of the basal septal and basal posterior walls (P = 0.001 and 0.02, respectively), and with a higher frequency of intracavity obstruction (21 vs. 9%; P = 0.04). Most patients (89%) exhibited at least one negative T-wave in the precordial leads; however, only 10% of patients had a negative T-wave of greater than 1.0 mV. We found that patients with an inverted T-wave larger than 0.4 mV (median) had a significantly increased LV ejection fraction (P = 0.03) compared with patients who had smaller or no negative T-waves. Conclusions: Among patients with apical HCM, nearly half do not have ECG evidence of LVH based on classic criteria and most do not have marked T-wave inversions. However, the majority did have at least a mild expression of negative T-waves.

scholarly journals Physiological ECG Value for Polish Half-Bred Anglo-Arab Horses

2012 ◽  
Vol 56 (4) ◽  
pp. 631-635 ◽  
Keyword(s):  
Heart Rate ◽  
P Wave ◽  
P Waves ◽  
T Wave ◽  
Duration Time ◽  
Qt Intervals ◽  
Electrocardiographic Examination ◽  
Electrocardiographic Findings ◽  
Almost All ◽  
T Waves

Abstract The electrocardiographic examination was performed in 33 training horses (2-16 years of age, 11 males and 22 females). Einthoven and precordial leads (I, II, III, aVR, aVL, aVF, CV1, CV2, CV4) were used. The ECG was performed in resting horses and immediately after exercise (10 min walk, 15 min trot, 10 min canter) using a portable Schiller AT-1 3-channel electrocardiograph, with a paper speed of 25 mm sec-1 and a sensitivity of 10 mm.mV-1. The heart rate, wave amplitudes, and duration time were estimated manually. All horses presented a significant increase in heart rate after exercise (rest 43.83 ±10.33 vs. exercise 73.2 ±14.8). QT intervals were significantly shortened in most of the leads. In resting horses, all P waves in the lead I were positive and almost all II, III and CV4 leads were positive. Simple negative P wave dominated in aVR and only simple negative T wave was found in the leads I. The biphasic shape was observed. After exercise, the amplitude of P and T waves rose, however, clear changes were not observed in wave polarisation and form. In the absence of specific racial characteristics of the electrocardiogram in the Polish Anglo- Arabians, electrocardiographic findings can be interpreted according to ECG standards adopted for horses.

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