Whipple's disease and papilledema. An unreported presentation

1969 ◽  
Vol 123 (1) ◽  
pp. 74-77 ◽  
Author(s):  
D. M. Switz
Keyword(s):  
Whipple’S Disease ◽  
Whipple's Disease

Scanning Electron Microscopy of Human Jejunum in Whipple's Disease

1977 ◽  
Vol 35 ◽  
pp. 354-355
Author(s):  
John H. L. Watson ◽  
C. N. Sun
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Basement Membrane ◽  
Lamina Propria ◽  
Brush Border ◽  
Whipple’S Disease ◽  
Whipple's Disease ◽  
Biopsy Specimens ◽  
Brush Borders ◽  
Scanning Electron

That the etiology of Whipple's disease could be bacterial was first suggested from electron micrographs in 1960. Evidence for binary fission of the bacteria, their phagocytosis by histiocytes in the lamina propria, their occurrence between and within the cells of the epithelium and on the brush border of the lumen were reported later. Scanning electron microscopy has been applied by us in an attempt to confirm the earlier observations by the new technique and to describe the bacterium further. Both transmission and scanning electron microscopy have been used concurrently to study the same biopsy specimens, and transmission observations have been used to confirm those made by scanning.The locations of the brush borders, the columnar epithelial cells, the basement membrane and the lamina propria beneath it were each easily identified by scanning electron microscopy. The lamina propria was completely filled with the wiener-shaped bacteria, Fig. 1.

A Possible Case of Whipple's Disease

1955 ◽  
Vol 29 (1) ◽  
pp. 120-133 ◽  
Author(s):  
Benjamin G. Oren ◽  
Richard M. Fleming
Keyword(s):  
Whipple’S Disease ◽  
Whipple's Disease

Whipple’s Disease

1963 ◽  
Vol 45 (1) ◽  
pp. 108-113 ◽  
Author(s):  
Jerome Bobruff ◽  
John DiBianco ◽  
Arthur Loebel ◽  
Victor W. Groisser
Keyword(s):  
Whipple’S Disease ◽  
Whipple's Disease

WHIPPLE'S DISEASE

1967 ◽  
Vol 2 (22) ◽  
pp. 985-989 ◽  
Author(s):  
R. C. Pirola ◽  
M. A. Mishkel ◽  
G. J. Macdonald ◽  
A. G. Liddelow
Keyword(s):  
Whipple’S Disease ◽  
Whipple's Disease

scholarly journals Seronegative Arthritis as a Complication of Whipple’s Disease

2021 ◽  
Vol 14 ◽  
pp. 117954762110177
Author(s):  
Rebecca DeBoer ◽  
Sahani Jayatilaka ◽  
Anthony Donato
Keyword(s):  
Rheumatoid Arthritis ◽  
Weight Loss ◽  
Abdominal Pain ◽  
Gastrointestinal Symptoms ◽  
Whipple’S Disease ◽  
Seronegative Arthritis ◽  
Whipple's Disease ◽  
Caucasian Male

Whipple’s disease (WD) is an uncommon cause of seronegative arthritis. WD is known for its gastrointestinal symptoms of diarrhea, weight loss, and abdominal pain. However, arthritis may precede gastrointestinal symptoms by 6 to 7 years. We describe a case of an 85-year-old Caucasian male with multiple joint complaints, not responsive to traditional treatments for conditions such as rheumatoid arthritis and osteoarthritis. We suggest that WD be considered for seronegative arthritis especially affecting large joints.

Whipple’s Disease: a Case Report Spanning 20 Years

2021 ◽  
Vol 3 (5) ◽  
pp. 1210-1214
Author(s):  
Isabel Furtado ◽  
Maria Trepa ◽  
Tomás Fonseca ◽  
Agostinho Sanchez ◽  
Diogo Rijo ◽  
...  
Keyword(s):  
Case Report ◽  
Whipple’S Disease ◽  
Whipple's Disease

scholarly journals Whipple’s Disease Affecting Ileal Peyer’s Patches: The First Case Report

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Sabah Sid’Amar ◽  
Giacomo Puppa
Keyword(s):  
Lymphoid Tissue ◽  
Diagnostic Yield ◽  
Clinical Investigation ◽  
Periodic Acid ◽  
Disease Diagnosis ◽  
Peyer's Patches ◽  
Peyer’S Patches ◽  
Whipple’S Disease ◽  
Whipple's Disease ◽  
First Case

Whipple’s disease is a rare chronic systemic bacterial infectious disease which can affect multiple organs, with a wide clinical spectrum encompassing many symptoms presenting in various forms and combinations. In the cases where the gastrointestinal tract is implicated, the more frequent localizations involve the small bowel, especially the duodenum. A case of a 67-year-old man who underwent clinical investigation after presenting with a progressive weight loss and showing a hypercapting right paracoeliac adenopathy at PET-CT scan is reported herein. A gastroscopy and a colonoscopy were done. The biopsies of the endoscopically normal ileal mucosa encompassed some submucosal Peyer’s patches. Histological examination of this lymphoid tissue revealed several foamy macrophages which turned out positive on periodic acid-Schiff special staining. Polymerase chain reaction of the microdissected lymph follicles allowed for confirming Whipple’s disease diagnosis. A targeted antibiotic treatment administrated to the patient led to a rapid clinical improvement. This finding of a previously unreported localization of infected macrophages in Whipple’s disease suggests that sampling the organized mucosal-submucosal lymphoid tissue may increase the diagnostic yield in endoscopic biopsies.

DERMATITIS HERPETIFORMIS ENTEROPATHY AND WHIPPLE'S DISEASE

2009 ◽  
Vol 188 (1-6) ◽  
pp. 301-302 ◽  
Author(s):  
Erik Myhre ◽  
Sverre Skrede ◽  
Egil Gjone
Keyword(s):  
Dermatitis Herpetiformis ◽  
Whipple’S Disease ◽  
Whipple's Disease
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